diff --git a/cmake/BuildParameters.cmake b/cmake/BuildParameters.cmake
index 8741c56203..6b2df0502b 100644
--- a/cmake/BuildParameters.cmake
+++ b/cmake/BuildParameters.cmake
@@ -116,6 +116,13 @@ elseif("${CMAKE_HOST_SYSTEM_PROCESSOR}" STREQUAL "arm64" OR "${CMAKE_HOST_SYSTEM
 		detect_cache_line_size()
 		list(APPEND PCSX2_DEFS OVERRIDE_HOST_CACHE_LINE_SIZE=${HOST_CACHE_LINE_SIZE})
 	endif()
+	
+	# Windows page/cache line size seems to match x68-64 
+	if(WIN32)
+		list(APPEND PCSX2_DEFS OVERRIDE_HOST_PAGE_SIZE=0x1000)
+		# Value of std::hardware_destructive_interference_size for ARM64 on MSVC toolset 14.40.33807
+		list(APPEND PCSX2_DEFS OVERRIDE_HOST_CACHE_LINE_SIZE=64)
+	endif()
 else()
 	message(FATAL_ERROR "Unsupported architecture: ${CMAKE_HOST_SYSTEM_PROCESSOR}")
 endif()
diff --git a/common/vsprops/common.props b/common/vsprops/common.props
index 179f5e35b1..d97da47b8d 100644
--- a/common/vsprops/common.props
+++ b/common/vsprops/common.props
@@ -29,6 +29,7 @@
       <IntrinsicFunctions>true</IntrinsicFunctions>
       <AdditionalIncludeDirectories>$(SolutionDir);$(ProjectDir);%(AdditionalIncludeDirectories);$(DepsIncludeDir)</AdditionalIncludeDirectories>
       <PreprocessorDefinitions>__WIN32__;WIN32;_WINDOWS;WIN32_LEAN_AND_MEAN;NOMINMAX;_CRT_NONSTDC_NO_WARNINGS;_CRT_SECURE_NO_WARNINGS;_CRT_SECURE_NO_DEPRECATE;_SCL_SECURE_NO_WARNINGS;_HAS_EXCEPTIONS=0;WINVER=0x0A00;_WIN32_WINNT=0x0A00;%(PreprocessorDefinitions)</PreprocessorDefinitions>
+      <PreprocessorDefinitions Condition="'$(Platform)'=='ARM64'">OVERRIDE_HOST_PAGE_SIZE=0x1000;OVERRIDE_HOST_CACHE_LINE_SIZE=64;%(PreprocessorDefinitions)</PreprocessorDefinitions>
       <PreprocessorDefinitions Condition="$(Configuration.Contains(Debug))">PCSX2_DEBUG;PCSX2_DEVBUILD;_SECURE_SCL_=1;%(PreprocessorDefinitions)</PreprocessorDefinitions>
       <PreprocessorDefinitions Condition="$(Configuration.Contains(Devel))">PCSX2_DEVEL;PCSX2_DEVBUILD;NDEBUG;_SECURE_SCL_=1;%(PreprocessorDefinitions)</PreprocessorDefinitions>
       <PreprocessorDefinitions Condition="$(Configuration.Contains(Release))">NDEBUG;_SECURE_SCL_=0;%(PreprocessorDefinitions)</PreprocessorDefinitions>