diff --git a/pcsx2-qt/Debugger/Breakpoints/BreakpointDialog.cpp b/pcsx2-qt/Debugger/Breakpoints/BreakpointDialog.cpp
index de993a6844..69176700f7 100644
--- a/pcsx2-qt/Debugger/Breakpoints/BreakpointDialog.cpp
+++ b/pcsx2-qt/Debugger/Breakpoints/BreakpointDialog.cpp
@@ -123,6 +123,11 @@ void BreakpointDialog::accept()
 			bp->cond.expression = expr;
 			bp->cond.expressionString = m_ui.txtCondition->text().toStdString();
 		}
+		else
+		{
+			bp->hasCond = false;
+			bp->cond = {};
+		}
 	}
 	if (auto* mc = std::get_if<MemCheck>(&m_bp_mc))
 	{
@@ -159,6 +164,11 @@ void BreakpointDialog::accept()
 			mc->cond.expression = expr;
 			mc->cond.expressionString = m_ui.txtCondition->text().toStdString();
 		}
+		else
+		{
+			mc->hasCond = false;
+			mc->cond = {};
+		}
 
 		int condition = 0;
 		if (m_ui.chkRead->isChecked())