diff --git a/pcsx2-qt/Settings/MemoryCardSettingsWidget.cpp b/pcsx2-qt/Settings/MemoryCardSettingsWidget.cpp
index 20cb7ce5b9..a5a98fa043 100644
--- a/pcsx2-qt/Settings/MemoryCardSettingsWidget.cpp
+++ b/pcsx2-qt/Settings/MemoryCardSettingsWidget.cpp
@@ -249,10 +249,12 @@ void MemoryCardSettingsWidget::renameCard()
 	if (newName.isEmpty() || newName == selectedCard)
 		return;
 
-	if (!newName.endsWith(QStringLiteral(".ps2")) || newName.length() <= 4)
+	const qsizetype extensionPos = selectedCard.lastIndexOf('.');
+	const QString extension(extensionPos >= 0 ? selectedCard.mid(extensionPos) : QString());
+	if (!newName.endsWith(extension, Qt::CaseInsensitive) || newName.length() <= extension.length())
 	{
-		QMessageBox::critical(
-			QtUtils::GetRootWidget(this), tr("Rename Memory Card"), tr("New name is invalid, it must end with .ps2"));
+		QMessageBox::critical(QtUtils::GetRootWidget(this), tr("Rename Memory Card"),
+			tr("New name is invalid, it must end with %1").arg(extension));
 		return;
 	}