diff --git a/apps/client/src/translations/en/translation.json b/apps/client/src/translations/en/translation.json
index ce41cca7b7..3a05cbfd37 100644
--- a/apps/client/src/translations/en/translation.json
+++ b/apps/client/src/translations/en/translation.json
@@ -1579,6 +1579,8 @@
     "enable-shadows": "Shadows",
     "enable-backdrop-effects": "Background effects for menus, popups and panels",
     "enable-smooth-scroll": "Smooth scrolling",
+    "enable-hardware-acceleration": "Hardware acceleration (GPU)",
+    "enable-hardware-acceleration-description": "Disable this if the app shows a blank window or has display glitches caused by your GPU drivers. Requires an app restart.",
     "app-restart-required": "Requires app restart"
   },
   "zoom_factor": {
diff --git a/apps/client/src/widgets/type_widgets/options/appearance.tsx b/apps/client/src/widgets/type_widgets/options/appearance.tsx
index 972f2da637..b93026dd99 100644
--- a/apps/client/src/widgets/type_widgets/options/appearance.tsx
+++ b/apps/client/src/widgets/type_widgets/options/appearance.tsx
@@ -658,6 +658,8 @@ function Performance() {
 
         {isElectron() && <SmoothScrollEnabledOption />}
 
+        {isElectron() && <HardwareAccelerationOption />}
+
     </OptionsSection>;
 }
 
@@ -673,6 +675,18 @@ function SmoothScrollEnabledOption() {
     />;
 }
 
+function HardwareAccelerationOption() {
+    const [ hardwareAccelerationEnabled, setHardwareAccelerationEnabled ] = useTriliumOptionBool("hardwareAccelerationEnabled");
+
+    return <OptionsRowWithToggle
+        name="hardware-acceleration-enabled"
+        label={t("ui-performance.enable-hardware-acceleration")}
+        description={t("ui-performance.enable-hardware-acceleration-description")}
+        currentValue={hardwareAccelerationEnabled}
+        onChange={setHardwareAccelerationEnabled}
+    />;
+}
+
 function MaxContentWidth() {
     const [maxContentWidth, setMaxContentWidth] = useTriliumOption("maxContentWidth");
     const [centerContent, setCenterContent] = useTriliumOptionBool("centerContent");
diff --git a/apps/desktop/src/main.spec.ts b/apps/desktop/src/main.spec.ts
index 3be7ce5b30..5cab3134e0 100644
--- a/apps/desktop/src/main.spec.ts
+++ b/apps/desktop/src/main.spec.ts
@@ -53,6 +53,8 @@ const h = vi.hoisted(() => ({
     isPrimaryInstance: true as boolean,
     allWindows: [] as unknown[],
     smoothScroll: "true" as string | null,
+    hardwareAcceleration: "true" as string | null,
+    disableHardwareAcceleration: vi.fn(),
     // When true, reading an option throws (simulates first run before the schema exists).
     dbUninitialized: false as boolean,
     isDbInitialized: true as boolean,
@@ -91,6 +93,7 @@ vi.mock("electron", () => {
         setName: (...a: unknown[]) => h.setName(...a),
         setUserTasks: (...a: unknown[]) => h.setUserTasks(...a),
         commandLine: { appendSwitch: (...a: unknown[]) => h.appendSwitch(...a) },
+        disableHardwareAcceleration: (...a: unknown[]) => h.disableHardwareAcceleration(...a),
         on: (event: string, cb: Handler) => h.appOn.set(event, cb),
         quit: (...a: unknown[]) => h.quit(...a),
         exit: (...a: unknown[]) => h.exit(...a),
@@ -183,6 +186,7 @@ vi.mock("@triliumnext/server/src/sql_provider.js", () => ({
             if (h.dbUninitialized) throw new Error("no such table: options");
             const values: Record<string, string | null> = {
                 smoothScrollEnabled: h.smoothScroll,
+                hardwareAccelerationEnabled: h.hardwareAcceleration,
                 locale: h.locale,
                 formattingLocale: h.formattingLocale
             };
@@ -264,6 +268,8 @@ function resetState() {
     h.isPrimaryInstance = true;
     h.allWindows = [];
     h.smoothScroll = "true";
+    h.hardwareAcceleration = "true";
+    h.disableHardwareAcceleration.mockClear();
     h.dbUninitialized = false;
     h.isDbInitialized = true;
     h.securitySettings = {};
@@ -406,6 +412,28 @@ describe("main() bootstrap", () => {
         expect(switches).not.toContain("disable-smooth-scrolling");
     });
 
+    // #10572: hardware acceleration is disabled before `ready` from the shared provider
+    // (same reason as smooth-scroll — core options aren't wired up yet).
+    it("disables hardware acceleration when the option is off", async () => {
+        setPlatform("darwin");
+        h.hardwareAcceleration = "false";
+        const { main } = await importMain();
+        await main();
+        expect(h.disableHardwareAcceleration).toHaveBeenCalled();
+    });
+
+    it("keeps hardware acceleration when the option is on, absent, or the DB has no schema yet", async () => {
+        for (const scenario of [{ value: "true" as string | null }, { value: null }, { value: "false" as string | null, uninitialized: true }]) {
+            resetState();
+            setPlatform("darwin");
+            h.hardwareAcceleration = scenario.value;
+            if (scenario.uninitialized) h.dbUninitialized = true;
+            const { main } = await importMain();
+            await main();
+            expect(h.disableHardwareAcceleration).not.toHaveBeenCalled();
+        }
+    });
+
     // Regression for #10559 (sibling of the smooth-scroll bug): the --lang switch is set
     // before core init from the same provider, so it must reflect the configured locale
     // instead of always falling back to "en".
diff --git a/apps/desktop/src/main.ts b/apps/desktop/src/main.ts
index e42ded163e..d39d83bc47 100644
--- a/apps/desktop/src/main.ts
+++ b/apps/desktop/src/main.ts
@@ -191,6 +191,12 @@ export async function main() {
     if (readDbOption(dbProvider, "smoothScrollEnabled") === "false") {
         app.commandLine.appendSwitch("disable-smooth-scrolling");
     }
+    // Lets users work around GPU driver incompatibilities that render a blank window
+    // (see #10572) without having to pass --disable-gpu on the command line. Like the
+    // switch above, this must run before `ready`.
+    if (readDbOption(dbProvider, "hardwareAccelerationEnabled") === "false") {
+        app.disableHardwareAcceleration();
+    }
 
     // The IPC provider just registers an `ipcMain.on` listener; no TCP socket
     // or session parser needed, so we can init it here (before startTriliumServer).
diff --git a/packages/commons/src/lib/options_interface.ts b/packages/commons/src/lib/options_interface.ts
index a77893b40c..1829c9ee00 100644
--- a/packages/commons/src/lib/options_interface.ts
+++ b/packages/commons/src/lib/options_interface.ts
@@ -138,6 +138,8 @@ export interface OptionDefinitions extends KeyboardShortcutsOptions<KeyboardActi
     shadowsEnabled: boolean;
     backdropEffectsEnabled: boolean;
     smoothScrollEnabled: boolean;
+    /** Desktop only: when disabled, Electron starts with GPU hardware acceleration turned off (workaround for GPU driver incompatibilities that cause a blank window). Requires an app restart. */
+    hardwareAccelerationEnabled: boolean;
     codeNoteTheme: string;
     codeNoteThemeMatchesApp: boolean;
     codeNoteThemeLight: string;
diff --git a/packages/trilium-core/src/routes/api/options.ts b/packages/trilium-core/src/routes/api/options.ts
index c2f505cdea..1274a8a8df 100644
--- a/packages/trilium-core/src/routes/api/options.ts
+++ b/packages/trilium-core/src/routes/api/options.ts
@@ -84,6 +84,7 @@ const ALLOWED_OPTIONS = new Set<OptionNames>([
     "motionEnabled",
     "shadowsEnabled",
     "smoothScrollEnabled",
+    "hardwareAccelerationEnabled",
     "backdropEffectsEnabled",
     "maxContentWidth",
     "centerContent",
diff --git a/packages/trilium-core/src/services/options_init.ts b/packages/trilium-core/src/services/options_init.ts
index 3bf9bbfafe..f446cd0ba1 100644
--- a/packages/trilium-core/src/services/options_init.ts
+++ b/packages/trilium-core/src/services/options_init.ts
@@ -244,6 +244,7 @@ const defaultOptions: DefaultOption[] = [
     { name: "shadowsEnabled", value: "true", isSynced: false },
     { name: "backdropEffectsEnabled", value: "true", isSynced: false },
     { name: "smoothScrollEnabled", value: "true", isSynced: false },
+    { name: "hardwareAccelerationEnabled", value: "true", isSynced: false },
     { name: "newLayout", value: "true", isSynced: true },
 
     // PDF