diff --git a/Source/Core/Core/Core.cpp b/Source/Core/Core/Core.cpp
index c64eb1e22e..91f1200f73 100644
--- a/Source/Core/Core/Core.cpp
+++ b/Source/Core/Core/Core.cpp
@@ -214,6 +214,9 @@ bool Init(std::unique_ptr<BootParameters> boot, const WindowSystemInfo& wsi)
 
   Host_UpdateMainFrame();  // Disable any menus or buttons at boot
 
+  // Issue any API calls which must occur on the main thread for the graphics backend.
+  g_video_backend->PrepareWindow(wsi);
+
   // Start the emu thread
   s_emu_thread = std::thread(EmuThread, std::move(boot), wsi);
   return true;
diff --git a/Source/Core/VideoCommon/VideoBackendBase.h b/Source/Core/VideoCommon/VideoBackendBase.h
index 83a74b0608..d1dada2247 100644
--- a/Source/Core/VideoCommon/VideoBackendBase.h
+++ b/Source/Core/VideoCommon/VideoBackendBase.h
@@ -43,6 +43,10 @@ public:
   virtual std::string GetDisplayName() const { return GetName(); }
   virtual void InitBackendInfo() = 0;
 
+  // Prepares a native window for rendering. This is called on the main thread, or the
+  // thread which owns the window.
+  virtual void PrepareWindow(const WindowSystemInfo& wsi) {}
+
   void Video_ExitLoop();
 
   void Video_BeginField(u32 xfb_addr, u32 fb_width, u32 fb_stride, u32 fb_height, u64 ticks);