diff --git a/src/retro/main_retro.c b/src/retro/main_retro.c
index f2be1e05f..dba1d8002 100644
--- a/src/retro/main_retro.c
+++ b/src/retro/main_retro.c
@@ -479,6 +479,11 @@ RETRO_API bool retro_load_game(const struct retro_game_info *game)
 
 	Retro_SetInputDescriptors();
 
+	/* The CPU, and with it the FPU emulation that save_fpu() and
+	 * restore_fpu() call into, is only reset by the first m68k_go() in
+	 * retro_run(), but a frontend may save or load a state before that. */
+	fpu_reset();
+
 	game_loaded = true;
 
 	return true;