diff --git a/configure b/configure
index 44c5637ea5..0af8f3c7e5 100755
--- a/configure
+++ b/configure
@@ -742,19 +742,21 @@ do_check_deps(){
 
         eval dep_all="\$${cfg}_deps"
         eval dep_any="\$${cfg}_deps_any"
+        eval dep_con="\$${cfg}_conflict"
         eval dep_sel="\$${cfg}_select"
         eval dep_sgs="\$${cfg}_suggest"
         eval dep_ifa="\$${cfg}_if"
         eval dep_ifn="\$${cfg}_if_any"
 
-        pushvar cfg dep_all dep_any dep_sel dep_sgs dep_ifa dep_ifn
-        do_check_deps $dep_all $dep_any $dep_sel $dep_sgs $dep_ifa $dep_ifn
-        popvar cfg dep_all dep_any dep_sel dep_sgs dep_ifa dep_ifn
+        pushvar cfg dep_all dep_any dep_con dep_sel dep_sgs dep_ifa dep_ifn
+        do_check_deps $dep_all $dep_any $dep_con $dep_sel $dep_sgs $dep_ifa $dep_ifn
+        popvar cfg dep_all dep_any dep_con dep_sel dep_sgs dep_ifa dep_ifn
 
         [ -n "$dep_ifa" ] && { enabled_all $dep_ifa && enable_weak $cfg; }
         [ -n "$dep_ifn" ] && { enabled_any $dep_ifn && enable_weak $cfg; }
         enabled_all  $dep_all || { disable $cfg && requested $cfg && die "ERROR: $cfg requested, but not all dependencies are satisfied: $dep_all"; }
         enabled_any  $dep_any || { disable $cfg && requested $cfg && die "ERROR: $cfg requested, but not any dependency is satisfied: $dep_any"; }
+        disabled_all $dep_con || { disable $cfg && requested $cfg && die "ERROR: $cfg requested, but some conflicting dependencies are unsatisfied: $dep_con"; }
         disabled_any $dep_sel && { disable $cfg && requested $cfg && die "ERROR: $cfg requested, but some selected dependency is unsatisfied: $dep_sel"; }
 
         if enabled $cfg; then
@@ -2379,7 +2381,8 @@ simd_align_32_if_any="avx"
 
 # system capabilities
 symver_if_any="symver_asm_label symver_gnu_asm"
-valgrind_backtrace_deps="!optimizations valgrind_valgrind_h"
+valgrind_backtrace_conflict="optimizations"
+valgrind_backtrace_deps="valgrind_valgrind_h"
 
 # threading support
 atomics_gcc_if="sync_val_compare_and_swap"
@@ -3119,10 +3122,10 @@ xv_outdev_extralibs="-lXv -lX11 -lXext"
 # protocols
 async_protocol_deps="threads"
 bluray_protocol_deps="libbluray"
-ffrtmpcrypt_protocol_deps="!librtmp_protocol"
+ffrtmpcrypt_protocol_conflict="librtmp_protocol"
 ffrtmpcrypt_protocol_deps_any="gcrypt gmp openssl"
 ffrtmpcrypt_protocol_select="tcp_protocol"
-ffrtmphttp_protocol_deps="!librtmp_protocol"
+ffrtmphttp_protocol_conflict="librtmp_protocol"
 ffrtmphttp_protocol_select="http_protocol"
 ftp_protocol_select="tcp_protocol"
 gopher_protocol_select="network"
@@ -3139,10 +3142,10 @@ libsmbclient_protocol_deps="libsmbclient gplv3"
 libssh_protocol_deps="libssh"
 mmsh_protocol_select="http_protocol"
 mmst_protocol_select="network"
-rtmp_protocol_deps="!librtmp_protocol"
+rtmp_protocol_conflict="librtmp_protocol"
 rtmp_protocol_select="tcp_protocol"
 rtmpe_protocol_select="ffrtmpcrypt_protocol"
-rtmps_protocol_deps="!librtmp_protocol"
+rtmps_protocol_conflict="librtmp_protocol"
 rtmps_protocol_select="tls_protocol"
 rtmpt_protocol_select="ffrtmphttp_protocol"
 rtmpte_protocol_select="ffrtmpcrypt_protocol ffrtmphttp_protocol"
@@ -3152,9 +3155,11 @@ sctp_protocol_deps="struct_sctp_event_subscribe struct_msghdr_msg_flags"
 sctp_protocol_select="network"
 srtp_protocol_select="rtp_protocol srtp"
 tcp_protocol_select="network"
-tls_gnutls_protocol_deps="gnutls !tls_schannel_protocol !tls_securetransport_protocol"
+tls_gnutls_protocol_conflict="tls_schannel_protocol tls_securetransport_protocol"
+tls_gnutls_protocol_deps="gnutls"
 tls_gnutls_protocol_select="tcp_protocol"
-tls_openssl_protocol_deps="openssl !tls_schannel_protocol !tls_securetransport_protocol !tls_gnutls_protocol"
+tls_openssl_protocol_conflict="tls_schannel_protocol tls_securetransport_protocol tls_gnutls_protocol"
+tls_openssl_protocol_deps="openssl"
 tls_openssl_protocol_select="tcp_protocol"
 tls_schannel_protocol_deps="schannel"
 tls_schannel_protocol_select="tcp_protocol"